Bioject® needle-free injection system provides significant advantages over needle-based syringes:

Greater patient acceptance and compliance (no needle-phobia)

Many patients have a strong aversion to needles and to physical discomfort. By eliminating the needle from the injection process, Bioject needle-free injectors significantly reduce the pain and discomfort associated with injections, improve the patient experience and, therefore, in many cases, bring about better compliance in situations where previously patients would not present themselves for therapy.

Superior safety by removing the potential of a needlestick injury, cross-contamination or delivery to unintended sites

Elimination of safety risk to healthcare workers from needlestick injuries or cross-contamination due to growing awareness in recent years of the danger of blood-borne pathogen transmission (WHO estimates 32 million Hepatitis B, 7 million Hepatitis C and 98,000 HIV new infections occur annually), needle safety has become a higher concern for hospitals, healthcare professionals and their patients.  It has been estimated that over 600,000 needlestick injuries occur annually among healthcare workers in the United States alone, with the average cost of investigating each needlestick injury being $500-$3000.  Healthcare workers experience significant fear, anxiety, and emotional distress following a needlestick injury.  The absence of needles from the injection process completely eliminates these needlestick injuries.  Additionally, Bioject’s sterile, single-use, disposable injection ‘nozzles’ prevent the cross-contamination shown to occur with earlier needle-free devices that employed re-usable injection nozzles.

Decreased risk of penetrating a patient’s vein or delivering medication to an unintended site

Techniques for delivering injectable medications to the desired sites using a needle and syringe are dependent on the selection of the proper needle, as well as on the skill of the healthcare worker in administering the medication to patients of all sizes, some of whom may not be cooperative due to needle-phobia.  These complications can be avoided by using the Bioject needle-free injection devices.

Potential improved efficacy due to ‘different’ drug distribution

 Typical injections with needle-based syringes deposits drugs in a pool in the desired tissue area.  This outcome is not always desirable since it may delay activity due to lack of dispersion within the tissue, requiring additional injections to reach a broader area, and/or causing greater side effects from local over-medication.  Bioject needle-free injection technology eliminates these problems by improving the dispersion of medication throughout the tissue compared needle-based devices.

Enhanced vaccine immune response

The Bioject needle-free injection technology has been known to enhance immunogenicity with certain commercially available vaccines as well as some vaccines that are currently under development

Injection reliability and technique is different with needle-free devices

  • Reliability: Bioject’s needle-free injection devices have been used widely in clinical practice for over 20 years. Bioject’s technology, based on the orifice size of the syringe, will determine the depth of penetration and not be based on technique as seen with a needle-syringe.
  • Repeatability: Needle-free injections are less dependent on doctor/nurse technique than those with needle and syringe, resulting in a more predictable penetration and distribution of the injected medication.

Faster injection time

Speed of Injection: Most injections are over in about 0.25 second. This rapid delivery both reduces patient discomfort and provides the capability for rapid mass immunizations.

Elimination of ‘sharps’ waste

No need for a “sharps” container for disposal of syringes and needles, thus reducing the cost of injection therapy.

Advantages of Bioject devices over other needle-free injectable delivery alternatives

  • Ability to inject adjustable doses (volumes).
  • Consistency and Reliability: Over 20 million needle-free injections given.
  • Broad Range of Capabilites:  Ability to deliver subcutaneous, intramuscular or intradermal injections simply by selecting appropriate syringes.
  • Potential vaccine dose sparing, as well as potential enhanced DNA vaccine delivery.

Injection safety and waste management

Even as health care systems in developing countries continue to grow stronger and better training and care reaches more people, the challenges associated with contaminated needles and medical waste continue to persist—exposing health workers, patients, and communities to unnecessary risk. For example, each year, an estimated 21 million hepatitis B, 2 million hepatitis C, and 260,000 HIV infections occur from accidental needlestick injuries and needle reuse—causing 1.3 million early deaths, a loss of 26 million years of life, and US$535 million in direct medical costs per annum globally.